Professor Tomoe was head of reasearch and one day he was in his lab showing off his experiment to some people including his daughter Hotaru. All of a sudden the experiment went wrong and everyone in the lab was killed including Professor Tomoe's daughter. The only surviver was Professor Tomoe. Later the Demon Master approched him with a little propostion. The Demon Master's propostion was that he would bring back Professor Tomoe's daugher back to life if Tomoe would give him his soul. Tomoe agreed. The Professor became head of the Death Busters. The evil in Tomoe was released when Sailor Neptune and Uranus summoned their talismans to defeat the Demon Master inside him.

Kaolinite was the first person to search for the talismans crystals. She was not part of the Witches 5. She was seemingly killed when the inner scouts attacked her with Sailor Planet Power, and Uranus's World Shaking knocked her off the roof. See appeared much later as a lab assistant to Tomoe, and a tormenter to Hotaru. She was the one to feed Hotaru Chibi-Usa's heart crystal. While Professure Tomeo congratulated her on finding such a pure heart, Mistress 9 let loose a blast that killed her.

Not much is known about Mistress 9. She hod one purpose in Sailor Moon S, to summon the Master Pharaoh Ninety. She possessed Hotaru. She was destroyed when Hotaru repossessed her body this happened when Sailor Saturn was discovered.

Eudial took over after Mistress 9 killed Kaolinite. She was the first or the Witches 5 that tryed to collect heart crystals for Tomoe She had a gun that extracted peoples heart crystals. She found that Uranus and Neptune had talisman crystals in their hearts. She was killed when Mimete rigged her car brakes and drove off a cliff.

Mimete took over after Edial was killed. She was the second of the witches send to find pure hearts When she found someone with a pure heart, she would let the demon swallow it and take it back to Tomoe. Mimete died when Tellu pulled the plug of the machine that helped her grow stonger.

Tellu was the third witch. She was in tune with nature and plants. She used plants to steal pure hearts. During a mission she was killed by one of her own plants.

Viluy was the fourth witch to try to find the three tailsmans. She knew alot about computers and used them to find and extract the pure hearts from people. She sent a computer to destroy the Senshi but Sailor Moon damaged it and it killed Viluy by mistake.

Cyprine and Pikurl were consitered one witch because they where twins. They were the last of the Witches 5. They were transporting crytals back to Tomoe when the Senshi arrived. There attacks went wrong and they killed each other.

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